This paper describes Unbend - a new method for measuring and correcting motions in cryo-EM images, with a particular emphasis on more challenging in situ samples such as lamellae and whole cells. The ...

Abstract: The Nelder-Mead simplex method is a well-known algorithm enabling the minimization of functions that are not available in closed-form and that need not be differentiable or convex.

Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, United Kingdom Department of Physics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, United Kingdom ...

For the analysis of simultaneous EEG-fMRI recordings, it is vital to use effective artifact removal tools. This applies in particular to the ballistocardiogram (BCG) artifact which is difficult to ...

This review presents the Analytical Quality by Design (AQbD) concept, an extension of Quality by Design (QbD), which was introduced in 2004 by the U.S. Food and Drug Administration (FDA) and approved ...

An increasing number of population genomic studies now try to infer complex models of population history using a number of whole-genome sequences sampled from multiple populations. A key technical ...

Industries require planning in transporting their products from production centres to the users end with minimal transporting cost to maximize profit. This process is known as Transportation Problem ...

This paper discusses techniques for solving discrete optimization problems using quantum annealing. Practical issues likely to affect the computation include precision limitations, finite temperature, ...